DNA Software (DNAS) was founded in year 2000 based upon the fundamental nucleic acid discoveries initially made by our President & CEO, Dr. John SantaLucia.

For over a decade, DNAS has integrated our world-leading expertise in nucleic acid thermodynamics into our suite of PCR design software. Our core technology has been further enhanced through a series of 9 NIH grants on studies ranging from PCR design, modified nucleotides, DNA kinetics, ThermoBLAST, Antisense design, and RNA 3D structure prediction. DNAS products have been licensed to leaders in pharma, biotech, agriculture, biodefense, regulatory agencies and academic institutions to help address the issues of false positives and complex multiplex design.

In addition to PCR design, DNA Software now offers qPCR analysis software to address the challenge of absolute quantification. qPCR CopyCount™ enables users to determine absolute DNA copy number down to a single copy of DNA using the fluorescence data from virtually any qPCR instrument (i.e. no special instrumentation is required). The software enables large scale data analysis and reduces associated costs by orders of magnitude. Applications of qPCR CopyCount include: gene expression, viral load, copy number variation, zygocity testing, non-invasive diagnostics, and Next Gen Sequencing.

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Thursday, 06 November 2014 22:15

DNA Software introduced the full commercial release of ThermoBLAST Cloud Edition (TB-CE). TB-CE provides a new standard for evaluating the target specificity of oligonucleotides.  Click here to learn more.  

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“We find it [Visual OMP™] makes very accurate and sometimes surprising (but true) predictions about binding efficiency in multiplexes...” David Whitcombe, Chief Scientific Officer, DxS Ltd, UK.
“It [Visual OMP™] is very powerful software when used for multiplexing design...” Chris Novak, Ambion
“I have designed over 10,000 PCR assays in my experience with DNA Software’s Visual OMP™ and found greater than 95% success rate when using it to design my assays compared to less than 20% success without it.” Dr. Eric Bruening, MolecularMD
“I have been using DNA [Software™] for a long time, at least 8 years. I want to have the best tools available and that is why we use it.” Dr. Nancy Schoenbrunner, Roche Molecular Systems
“I am a long-term user of Visual OMP™. I like this program very much because it provides a solid scientific basis for oligo design and cuts the development time by more than half.” Olga Budker, longtime Visual OMP user
“In my experience, DNA Software™ saved me 75% of my oligo costs.” Helen Minnis, Wave 80
“DNA [Software™] has passed my tests. I’ve recommended it [Visual OMP™]. It performs extremely well.” Dr. Ned Sekinger, Luminex Corporation
“Learning to use the program [Visual OMP™] is time well spent, and the support staff at DNA Software is always ready and able to help” Dr. Sue J. Kohlhepp, Providence Portland Medical Center.