July 10, 2003

DNA Software Launches Visual OMP™ 3 for Designing and Simulating DNA- and RNA-based Assays

Genomic researchers can now design more specific and sensitive nucleic acid experiments and reduce trial and error bench work

Ann Arbor, Mich. – July 10, 2003 – DNA Software, a leading provider of software, scientific consulting and lab research for genomic researchers, announced today the launch of Visual OMP™ 3. This product is the latest advancement of the company’s proprietary Oligonucleotide Modeling Platform™ (OMP™) which provides researchers with an in silico laboratory environment for designing PCR and microarray based experiments. With Visual OMP™ 3, genomic researchers are able to design more sensitive and specific assays and reduce trial and error bench work.

“Visual OMPTM 3 provides researchers with the ability to automatically design multiple sets of primers and probes that are optimized for specific experiments yet reduce cross-hybridization and mis-hybridization between oligos and targets,” stated Don Hicks, COO and vice president of DNA Software.

Unlike existing software products, DNA Software’s proprietary ThermoBlast algorithms evaluate the thermodynamic energy associated with every possible competitive reaction and predicts the concentration each will form in a reaction. Probes and primers can be tailored to emphasize specificity, sensitivity, melting temperature or length. Visual OMP™ 3 is the outcome of nearly ten years research by Dr. John SantaLucia, chief science officer of DNA Software and associate professor at Wayne State University.

“We’ve been using OMP to solve real-world assay design problems on a consulting basis for over two years. Visual OMP™ 3 brings together all that we’ve learned about using in silico technology to design better assays with less effort,” noted Mark Kielb, president of DNA Software.

Visual OMP™ 3’s integrated folding engine allows scientists the ability to visualize target and oligo structure much faster than other available products and includes the first sequence dependent hairpin model. Visual OMP™ 3’s in silico laboratory is further enhanced by integration of the third-party tools BLAST and ClustalW.

DNA Software also offers a OMP Developer Edition™ (OMP DE™), that allows programmers to integrate OMP™ into high-throughput applications. OMP DE™ provides an application programming interface (API) for scripting OMP™ access and linking it with existing databases and supports client/server, distributed (GRID), and network installation.

DNA Software’s Visual OMP™ 3 is available for the Windows operating environment. OMP DE™ is available for Windows, Linux, UNIX, and Alpha operating systems.

Academic pricing is available for all products. For more information or to schedule a demonstration, please contact DNA Software at +1 (734) 222-9092.

About DNA Software, Inc.
DNA Software, Inc. combines science and software to enable industrial genomics through advances in technologies based on nucleic acids. The company’s first software platform, OMP™ (Oligonucleotide Modeling Platform™) models in silico the folding and hybridization of single-stranded nucleic acids with great accuracy. The company combines OMP™ with scientific consulting, custom software development, and custom laboratory research to deliver state-of-the-art support for designing and developing of nucleic acid based technologies.

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Thursday, 06 November 2014 22:15

DNA Software introduced the full commercial release of ThermoBLAST Cloud Edition (TB-CE). TB-CE provides a new standard for evaluating the target specificity of oligonucleotides.  Click here to learn more.  

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“We find it [Visual OMP™] makes very accurate and sometimes surprising (but true) predictions about binding efficiency in multiplexes...” David Whitcombe, Chief Scientific Officer, DxS Ltd, UK.
“It [Visual OMP™] is very powerful software when used for multiplexing design...” Chris Novak, Ambion
“I have designed over 10,000 PCR assays in my experience with DNA Software’s Visual OMP™ and found greater than 95% success rate when using it to design my assays compared to less than 20% success without it.” Dr. Eric Bruening, MolecularMD
“I have been using DNA [Software™] for a long time, at least 8 years. I want to have the best tools available and that is why we use it.” Dr. Nancy Schoenbrunner, Roche Molecular Systems
“I am a long-term user of Visual OMP™. I like this program very much because it provides a solid scientific basis for oligo design and cuts the development time by more than half.” Olga Budker, longtime Visual OMP user
“In my experience, DNA Software™ saved me 75% of my oligo costs.” Helen Minnis, Wave 80
“DNA [Software™] has passed my tests. I’ve recommended it [Visual OMP™]. It performs extremely well.” Dr. Ned Sekinger, Luminex Corporation
“Learning to use the program [Visual OMP™] is time well spent, and the support staff at DNA Software is always ready and able to help” Dr. Sue J. Kohlhepp, Providence Portland Medical Center.