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August 20, 2009

DNA Software, Inc. Completes Assay Design and Optimization Training at Its New Offices in Downtown Ann Arbor, MI

Ann Arbor, MI – August 20th, 2009 – DNA Software, Inc. just completed a successful, two day training at its new offices in downtown Ann Arbor, MI.

The first day of training focused on the science of nucleic acid thermodynamics, basic and advanced function in Visual OMP™, advanced assay design including multiplex PCR and microarrays, as well as high-throughput and scripting applications for DNA Software’s Developer Edition™ products.

Each class participants received a free trial license to Visual OMP™ with the ThermoBLAST™ and Modifieds™ modules and performed several hands-on case studies on assay development.

The second day of training included an overview of DNA Software’s newly released Modifieds™ module. This new add-on feature for Visual OMP™ allows users to simulate and develop assays that incorporate modified nucleotides. It contains thermodynamic parameters for LNA, PNA, Morpholino, DeoxyU, Inosine, Iso-C, and Iso-G in the context of DNA and RNA. The ThermoBLAST™ module, algorithm, and science were also reviewed during the second day. ThermoBLAST™ represents a much more accurate method than BLAST to check your assay designs against whole genomes to ensure they do not mishybridize to unintended targets. As with previous training classes, part of the class was dedicated to customers’ specific research projects.

Given the success of this class DNA Software is proposing a class in Amsterdam in mid-October and another one in Ann Arbor in later November. If you are interested in joining us for either of these training sessions, please contact: This email address is being protected from spambots. You need JavaScript enabled to view it. or call +1 734 222 9080.

About DNA Software, Inc.
DNA Software, Inc. was founded in 2000 to commercialize the advances in nucleic acid chemistry discovered by world-renowned expert Dr. John SantaLucia, Jr. (the company’s Chief Scientific Officer). DNA Software’s technologies have become the standard of excellence for nucleic acid research and diagnostics development.

DNA Software is a unique software company considering that it conducts original wet lab research. The company’s software programs are the most accurate and comprehensive tools available because their advanced algorithms and models are driven by a large database of thousands of diverse, wet lab-derived, experimental results. DNA Software’s tools correctly design and simulate complicated experiments on the first attempt. Customers can simulate thousands of experiments with the software before running a single experiment in a wet lab. Thus, DNA Software’s technologies save customers significant time, resources, and money that would have been wasted on trial-and-error experimentation.

DNA Software offers contract research, custom software development, commercial web applications, and scientific consulting for nucleic acid research. The company also licenses packaged software tools that help scientists quickly and accurately develop new assays, diagnostics, and therapeutics. OMP™ (Oligonucleotide Modeling Platform™), the core engine that runs all of DNA Software’s tools, models in silico the folding and hybridization of nucleic acids with exceptional accuracy. Visual OMP™ is a platform program for the design, simulation, and analysis of probes/primers, RT-PCR, qPCR, Multiplex PCR, Taqman, Beacons, Scorpions, Microarrays, SNP detection, FRET assays, RNAi, LATE-PCR, plus new formats. OMP Developer EditionTM (OMP DE™) brings customizable, command line, high-throughput computing power to large assay design projects or enterprise applications. ThermoBLAST™ quickly and accurately scans DNA and RNA against genome databases, identifies all off-target hybridizations, and tells you if these mishybridized probes/primers are extensible by polymerase. Modifieds™ allows you to simulate and develop assays that incorporate modified nucleotides (e.g. LNA, PNA, Morpholino, DeoxyU, Inosine, Iso-C, and Iso-G).

The company has recently expanded its original DNA and RNA-based, molecular biology solutions to include modified nucleotides, oligonucleotide kinetics, and structural biology.

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Thursday, 06 November 2014 22:15

DNA Software introduced the full commercial release of ThermoBLAST Cloud Edition (TB-CE). TB-CE provides a new standard for evaluating the target specificity of oligonucleotides.  Click here to learn more.  

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“We find it [Visual OMP™] makes very accurate and sometimes surprising (but true) predictions about binding efficiency in multiplexes...” David Whitcombe, Chief Scientific Officer, DxS Ltd, UK.
“It [Visual OMP™] is very powerful software when used for multiplexing design...” Chris Novak, Ambion
“I have designed over 10,000 PCR assays in my experience with DNA Software’s Visual OMP™ and found greater than 95% success rate when using it to design my assays compared to less than 20% success without it.” Dr. Eric Bruening, MolecularMD
“I have been using DNA [Software™] for a long time, at least 8 years. I want to have the best tools available and that is why we use it.” Dr. Nancy Schoenbrunner, Roche Molecular Systems
“I am a long-term user of Visual OMP™. I like this program very much because it provides a solid scientific basis for oligo design and cuts the development time by more than half.” Olga Budker, longtime Visual OMP user
“In my experience, DNA Software™ saved me 75% of my oligo costs.” Helen Minnis, Wave 80
“DNA [Software™] has passed my tests. I’ve recommended it [Visual OMP™]. It performs extremely well.” Dr. Ned Sekinger, Luminex Corporation
“Learning to use the program [Visual OMP™] is time well spent, and the support staff at DNA Software is always ready and able to help” Dr. Sue J. Kohlhepp, Providence Portland Medical Center.